Plasma therapy for non-cicatrical alopecia
Since 1970, plasma therapy has acquired an important role both in the process of tissue repair, hemostasis, and the acceleration of peptic ulcer diseases and regeneration processes. In recent years, plasma therapy has acquired a special role in the hair loss treatment algorithm.
During plasma therapy, platelet-rich plasma is used, which is rich in growth factor. The growth factor provides angiogenesis, extracellular matrix remodeling, cell proliferation and differentiation. Based on this, plasma therapy is used in many areas of medicine, such as: orthopedics, maxillofacial surgery, plastic surgery, dermatology.
Plasma that is used during plasma therapy is enriched with platelets (approximately 1 ml. Of platelets / μL). The regenerative property of plasma therapy depends on the level of released growth factor.
Platelet alpha granules contain a growth factor (GF), after activation of which they are responsible for initiating and maintaining a therapeutic effect. It is known that the composition of platelet-rich plasma, in addition to the growth factor, includes other protein molecules, such as: Adhesin, Chemokine, and other molecules that contribute to the processes of regeneration and proliferation.
Recently, many clinical studies on the effectiveness of plasma therapy during non-scar alopecia have been conducted. Of particular interest was the mechanism of the effect on the hair follicle of growth factors that make up the plasma.
Growth factors can be of several types:
Platelet growth factor (PDGF);
Transformation Growth Factor (TGF-b);
The growth factor of endothelin blood vessels (VEGF), which by their isomorphs bind to the corresponding receptors and ensure tissue angiogenesis.
They act on the stem cells from which epidermal cells and sebaceous glands of ectodermal origin are formed, found in the root of the hair follicle and on the papillary cells (dermal papilla) in the matrix, which leads us to stimulate hair growth, to activate the existing so-called. “Sleeping follicle.”
Plasma therapy is carried out 1 time per month.
It is desirable to conduct 9 procedures per year according to the appropriate scheme.
Before the procedure, it is desirable to conduct a general blood test, so that the trichologist will select a treatment regimen for you.